California Assembly Speaker Anthony Rendon is one of the most powerful political figures in our state. With term limits now allowing folks like him to serve longer in one chamber, he is likely to stay that way for years to come. We sat down with Rendon to talk about some of the critical issues facing lawmakers and Californians in what is expected to be one of the most turbulent years in modern history.

It seems 39 percent of millennials would rather disclose a preexisting sexually transmitted disease to a potential partner than reveal their debt, according to a survey of 2,000 millennials SoFi conducted, using online poller Survey Monkey. In addition, the survey found that serious debt was the second-biggest romantic deal-breaker, after workaholism.

Seven years after passage of the Affordable Care Act created a new world order in health insurance, it all may be upended. With a new administration in Washington, all or parts of Obamacare could be repealed and replaced. All the while, premium increases have continued apace: 

TrueNorth reflects the growing trend of studios and gyms offering stationary cycling — or spin, as the workout is also called — with dozens of these classes available throughout the Sacramento region.

Last quarter was the slowest three-month period for drug company initial public offerings in four years, according to Bloomberg data. And in all of 2016, only 36 biotech and pharmaceutical companies went public in the U.S., according to data gathered by Bloomberg, compared with 68 in 2015 and a record 85 in 2014.

Last year was one for the history books. But as we start the new year, we wanted to take one last look back at some of our best-performing and most-read articles of 2016. Take a look and see if you missed any of our greatest hits — or if something might deserve a second read.

Venture Catalyst is one part of a multipronged effort at the school that its leaders say is helping turn university research into companies that produce world-changing technologies. The school has facilitated a total of 49 startups in the last four fiscal years, up from 18 in the four years prior.

Technically, Atocera Inc. is the result of a shaving accident.

Back in 2012, Saif Islam, a UC Davis professor of electrical and computer engineering, was in the campus labs building silicon micro-walls for solar panels. During the process of cutting semiconductor material into small slices, something unexpected happened.

Each month, Comstock’s online features a different Startup of the Month. As 2016 comes to a close, we take one last look at these startups to see how they stack up.

But Anpac Bio’s major innovation is not about where, but when. Catching cancer in the earliest stages has been Yu’s goal since the company launched in 2010. With so much medical research focused on treatment and imaging, he set his sights on early detection as the key to prevention. His ideas were unconventional.