The fate of the Affordable Care Act is again on the line Tuesday, as a federal appeals court in New Orleans takes up a case in which a lower court judge has already ruled the massive health law unconstitutional.

The California agency that regulates doctors is investigating at least four physicians for issuing questionable medical exemptions to children whose parents did not want them immunized.

Ann Manganello survives entirely off her Social Security stipend: $1,391 a month.

That doesn’t amount to much in the pricey desert enclave of Palm Springs, Calif. — especially for someone who contends with a host of expensive medical problems, including a blood vessel disorder, complications from a recent stroke and frequent bouts of colitis.

Cities across the country struggle with how to revitalize historically disenfranchised neighborhoods. An interesting and successful model — using public education, economic development and self-empowerment to drive change — has had a profound impact on a local underserved community.

When HealthCare.gov — the Affordable Care Act’s health insurance exchange website — went live in 2013, it was slow, buggy and hard to navigate — a digital mess. Two weeks later, three programmers in the Bay Area launched HealthSherpa.com, an alternative website to help online shoppers understand their options under the ACA and see plans and prices quickly.

Throughout the region, public and private-sector players are rethinking women’s health, expanding and diversifying their approach to maternal and infant health.

What are employers expected to do for employees when the air quality is dangerous? Are we legally obligated to close when the air quality is so bad?

One area health system is among a small group of providers nationwide trying something different. In September 2014, Dignity Health implemented a system in four Sacramento-area hospitals designed to bring more satisfaction to patients and families after adverse medical events while boosting patient safety.

In one of his first official actions, Gov. Gavin Newsom has directed that state agencies, including the one that oversees Medi-Cal, negotiate as a block to demand prescription drug makers lower their prices.

Sutter Health opened its new state-of-the-art Senior Care PACE medical and recreational complex in the River District on Dec. 10. The 45,000-square-foot space can accommodate a total of 1,000 patients per day.