Effective leaders don’t come from one mold. The women featured below have excelled in nontraditional industries due to their talent, vision, perseverance and the (sometimes unlikely) mentors who guided their trajectory. They shared their stories with us — where they started, their rise to leadership and their thoughts on mentoring the next generation of powerful women.

It was time for Lola’s afternoon nap. Her mother, Melissa Logue, was all set to read Thomas the Tank Engine. But as she walked to her 3-year-old daughter’s bedroom, she dropped the book. Her right side felt numb and a sharp pain suddenly seized her head. She couldn’t speak.

This year’s list features innovators, disruptors and creators who are invigorating our cities and challenging the status quo. The impact they’ll make in our local communities and beyond will help define our future.

Imagine a world where you’re hooked to a system of electrodes that scans your skull, hunts for patterns, and then scores your IQ, emotional intelligence, ability to communicate, capacity for judgment and potential to be a good leader. Then imagine that the therapist says, “The bad news is that your score should be higher. The good news is that I can get it there by helping you physically change your brain.”

There is an old jest that says the fastest way for a business to run off its customers is to adhere to the motto, “In God we trust; all others must pay cash.” But for Kimberly Cargile, director of the East Sacramento medical marijuana dispensary, A Therapeutic Alternative, cash and carry is her only option. And it really is no laughing matter.

In the coming months, Chris Johnson will ask a lot of his employees, whose average age is just 24 years old. He expects to do $30 million in retail sales this third year of manufacturing, recently signed a powerful licensing deal with Disney’s Marvel, and plans to expand from the four products currently on shelves to more than 100 next year. But Johnson’s hiring strategy emphasizes passion over experience, something he says his team has in spades.

Wine tasting is often an experience shared only by the taster and pourer. A brewery tasting room, however, needs to facilitate the gregariously social aspects of craft beer, making space for interaction and mingling. Room to brew, room to chat and room to sample flights of beer make for highly dynamic spaces that bring to life the distinct personalities of brewers and their art.

Many of us are familiar with Woodroof’s plight — it was the subject of the critically acclaimed movie “The Dallas Buyers Club.” But while Hollywood took many liberties in telling his story, Woodroof’s real-life dilemma is one still being shared by many terminally ill people today. That struggle is also at the heart of a movement to allow those patients access to drugs the FDA has not authorized.

In the past five years, 57-year-old Elaine Walker has lived in four cities: Washington D.C., two in Northern California and now Orlando, Fla. And in all four, she lived in the same house.That’s because it’s a farmhouse on wheels.

This is Chef Breedlove’s third attempt, more or less, at branding a mobile food business, and this time he’s letting his personality and mad-scientist approach to mobile food define the brand.